Category: Reproductive Endocrinology

Monitor: 18

18 - INFLUENCE OF GESTATIONAL WEIGHT GAIN AND PRE-PREGNANCY BODY MASS INDEX ON BIRTH WEIGHT

Saturday, Apr 27
11:30 AM – 12:00 PM

Objective :

To compare gestational weight gain and prepregnancy body mass index as predictors of birthweight


Methods :

The pregnant women were recruited weekly from antenatal clinic at the Lagos University Teaching Hospital (LUTH), Lagos, Nigeria. The study was a prospective open cohort study carried out from March to November 2017. Ethical approval was obtained from LUTH Ethical Committee. All pregnant women had 75g Oral Glucose Tolerance test (OGTT) at 24 to 28 weeks gestation. The women were followed up till delivery. The data obtained were prepregnancy weight, height, risk factors for gestational diabetes mellitus, gestational weight at 37 weeks gestation and weight of newborn at delivery. The data were presented as median, percentages, chi square, odd’s ratio and correlation coefficient. The p value ≤ 0.05 was considered significant.  


Results :

Ninety pregnant women were recruited in the course of the study. Six were lost to follow up because they delivered outside the LUTH. Using prepregnancy BMI, 14 women were obese, 35 were overweight and 41 had normal body mass index. Gestational weight gain had a stronger positive linear correlation with birthweight than prepregnancy BMI and prepregnancy weight. Using the Institute of Medicine classification of weight gain based on BMI, gestational weight gain was higher in women with obese prepregnancy BMI. The odd’s ratio for occurrence of macrosomia comparing GWG and prepregnancy BMI were 4.26 and 4.25 respectively


Discussion :

Gestational weight gain and prepregnancy BMI both had a positive linear relationship with birthweight. Gestational weight gain had stronger relationship than prepregnancy BMI with birth weight independent of glucose intolerance status. The higher the gestational weight gain, the more the risk of delivery of macrosomic baby.


Conclusion :

Gestational weight gain had a stronger influence on birthweight. Women should be counseled on avoidance of excessive weight gain in pregnancy. Also, they should be encouraged on attainment of normal BMI prior to pregnancy.

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Bolanle OLAJUMOKE. Okunowo

Senior registrar
Lagos University Teaching Hospital , Lagos; Nigeria
Agege, Lagos, Nigeria

Senior registrar

Ifedayo Odeniyi

Senior lecturer,
College of Medicine, University of Lagos, Nigeria, Lagos, Nigeria

Senior lecturer

Oluwarotimi Olopade

Consultant
Lagos University Teaching Hospital , Lagos; Nigeria

LUTH

Olufemi Fasanmade

Associate Professor of Medicine
College of Medicine, University of Lagos, Nigeria

Associate Professor of Medicine

Omololu Adegbola

Associate Professor of Medicine
College of Medicine, University of Lagos, Nigeria, Lagos, Nigeria

Associate Professor College of Medicine, University of Lagos, NIgeria

Adeyemi Okunowo

lecturer,
College of Medicine, University of Lagos, Nigeria, Lagos, Nigeria

Lecturer, College of Medicine, University of Lagos, NIgeria

Augustine Ohwovoriole

Professor of Medicine/ Endocrinologist
College of Medicine, University of Lagos, Nigeria, Lagos, Nigeria

Professor College of Medicine/ Endocrinologist, University of Lagos, NIgeria