Professor of Medicine, Saint Michael’s Hospital, Toronto, ON, Canada

I have obtained peer reviewed and non-peer reviewed grants (mostly Phase II and III pharmaceutically funded multi-centre national and international studies) as principal, co-principal or co-investigator. These studies have investigated the effects of various new drugs on diabetes control, hyperlipidemia and prevention or treatment of diabetes complications. I have been particularly interested in the nutritional management of diabetes with other colleagues in the division (Jenkins, Vuksan, Wolever): we have promulgated the concept of the glycemic index of foods and the importance of meal frequency as therapeutic principles. Our more recent studies have moved into the area of disease prevention, e.g. diabetes, cardiovascular disease and osteoporosis using different nutraceuticals as well as drugs. We have also been investigating the potential efficacy of herbal and alternative medicine remedies, e.g. ginseng, Konjac-mannan.

Our group has been involved in a number of national and international osteoporosis studies in epidemiology, as well as phase III clinical drug trials. We collaborate widely with the Women’s Health Centre, rheumatology, physiatry, orthopedics and other disciplines within the hospital and city-wide. I am the director of the Toronto Centre of the CIHR-funded Canadian Multicentre Osteoporosis Study (CaMOS). The osteoporosis centre (of which I am the director) is a focus for clinical and epidemiologic research, as well as graduate and postgraduate education and general patient care.