Category: Thyroid

Monitor: 33

33 - MALIGNANCY RATE OF THYROID CANCER FROM FINE NEEDLE ASPIRATION CYTOLOGIES IN CALMETTE HOSPITAL, CAMBODIA

Thursday, Apr 25
11:00 AM – 11:30 AM

Objective :

Thyroid cancer is one of the less explored cancers in Cambodia. Mostly the data about thyroid cancer were based on the surgical pathology reports. The technique of fine needle aspiration (FNA) was performed for the first time in the country at Calmette hospital. There was no previous thyroid cancer data based on the FNA.

The aim of this study is to evaluate the malignancy rate of thyroid cancer based on fine needle aspiration (FNA) at Calmette hospital, Cambodia. 


Methods : We retrospectively analyzed the 197 results of the fine needle aspirations performed at Calmette hospital from January 1st 2015 to October 31st 2018. All the patients had solitary or multiple thyroid nodules, with the size > 10mm. The FNA results were based on the Bethesda classification. And the malignancy criteria in our study included the Bethesda category IV, V and VI.


Results :

In our study the patients were relatively young. The age group < 35 year olds 35.0%, 35-44 year olds 20.3%, 45-55 year olds 17.7% and > 55 year olds 27.0%. And most of the patients were female (female 89.4% vs male 10.6%). Most of the patients had multiple nodules (multiple nodules 57.4% vs solitary nodule 42.6%). And 68.5% of the cases the nodules’ sizes was 10-30mm compared to 31.5% of the case the nodules’ size >30mm.


Among the 197 FNA samples, we found 20 cases of malignancy, representing 10.1%. And it was significantly higher in the group who were less than 35 year olds compared to other groups (p 0.02). 


Discussion : In literature, the fine needle aspiration was a safe and effective method to screen for thyroid cancer. Nevertheless, in Cambodia this technique has been performed for the first time by endocrinologists and anatomopathologists. 

In present study, since we retrospectively analysed the request forms of patients from the anatomopathology laboratory there were insufficent patients' history and clinical symptoms to analyzed the risks of malignancy.


Conclusion :

The result of our study showed that the rate of thyroid cancer was relatively high among young patients who had thyroid nodules. A multicenter data should be collected to estimate the national prevalence of thyroid cancer. 

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Satha Sum

Chief of Internal Medicine Unit
Calmette hospital
Phnom Penh, Cambodia

Dr. SUM Satha is a specialist in Endocrinology. He obtained his diploma in Internal Medicine from the University of Health Sciences, Cambodia in 2006. He subsequently received 2 years training in Endocrinology in a Strasbourg University Hospital, France from 2006 to 2008.

Sereyvuth Chhe

Internist
Calmette hospital
PHNOM PENH, Cambodia

Dr. CHHE Sereyvuth is an internist at Calmette hospital.

Sophanara Min

Endocrinologist
Calmette hospital
PHNOM PENH, Cambodia

Dr. MIN Sophannara is an endocrinologist at Calmette hospital.

Linat Kong

Endocrinologist
Calmette hospital
PHNOM PENH, Cambodia

Dr. KONG Linat is an endocrinologist at Calmette hospital.

Hokban Sor

Endocrinologist
Calmette hospital
PHNOM PENH, Cambodia

Dr. SOR Hokban is an endocrinologist at Calmette hospital.

Silong Yat

Endocrinologist
Calmette hospital
PHNOM PENH

Dr. YAT Silong is an endocrinologist at Calmette hospital.

Vanny Koy

Chief of Medical Affairs
Calmette hospital
PHNOM PENH

Pr. KOY Vanny is an endocrinologist at Calmette hospital.

Michel Pluot

Anatomopathologist
Calmette hospital
PHNOM PENH, Cambodia

Pr. PLUOT is a professor of anatomopathology.