To document the pattern of thyroid disorders as seen in endocrinology clinic of Olabisi Onabanjo University Teaching Hospital ,Sagamu over a two –year period.
This was prospective study involving all patients presenting to the Endocrine,Diabetic and Metabolic unit (EDM) of Department of Medicine between January 2016 to December 2017. Socio-demographic, clinical history and anthropometric indices were recorded. Clinical and thyroid examination performed. Blood samples in the fasting state were analyzed for thyroid function tests including TSH, FT4, FT3. Thyroid autoantibodies and thyroid scan results were collected. Patients were grouped accordingly into Euthyroid, hypothyroid and Thyrotoxic. Descriptive data analysis was by SPSS 21.
The total number of thyroid cases seen during 2 year period review was ninety- three (93). This formed 13.64% of total endocrine consultations (682 patients) during the period of review. Goitrous enlargement constituted 77.4 %( 72), with age ranging from 15 to 78 years, mean age 37.6 (13.6) years, with female preponderance of 81.7% (Female: Male ratio 4.5: 1). Thyrotoxicosis 72 (77.40%) was the commonest occurring thyroid disorder seen among these patients, of which primary hyperthyroidism from Graves’ disease was the most prevalent 50 (69.44%%),followed by toxic multinodular goitre 12(16.67%), toxic solitary nodular goiter 5 (6.94%) and others 5 (6.95 %) . Hypothyroidism constituted 10(10.75%) and others 11(11.85%) of all thyroid cases.The major complications seen were heart failure 26.9%, thyroid storm 3.23% and obstructive /compressive features 5.4% among others.
Discussion : Our results showed the prevalence of thyroid disorders was 13.74 % of the total endocrine cases seen over 2 year review. Thyroid disorders commonly affected age group 21-50years with a female prepondence. Thyrotoxicosis /Hyperthyroidism was the commonest endocrine disoder seen primarily due autoimmune aetiology- Graves disease , and followed by toxic nodular goitres. The major cause of morbidity was heart failure and arrthymias due late presentation
Autoimmune thyroid disease predominantly graves disease remains the most common thyroid disorder among patients presenting in a tertiary endocrine clinic in sub-urban region of Nigeria.
Ayotunde Ale– Lecturer /Consultant Endocrinologist, Olabisi Onabanjo University Teaching Hospital , Sagamu.Nigeria, Somolu, Nigeria
Opeyemi Aloro– Medical officer, NMA,ARD, Ibadan, Oyo, Nigeria
Ayanbola Adepoju– Dr Adepoju I. Ayanbola, Endocrine and Metabolism Society of Nigeria, Sagamu, Ogun, Nigeria
Lecturer /Consultant Endocrinologist
Olabisi Onabanjo University Teaching Hospital , Sagamu.Nigeria
Dr Ale A.O . I am a scientist, researcher and endocrinologist . i love teaching and research. i pioneered bone studies in hyperthyroidism in Nigeria among others
Ibadan, Oyo, Nigeria
Dr Aloro Opeyemi Bamise had her elementary education at IMG olubadan, where she had her primary school leaving certificate in 1998. She proceeded to Oladipo Alayande school of science, and had her WASSCE in 2004. She had her tertiary Education at Ladoke Akintola University of Technology and obtained MB;BS in medicine and surgery, in the year 2016. She did her housemanship at Olabisi Onabanjo University Teaching hospital sagamu between 2017 and 2018. She had some working experiences in some private hospital as a Medical officer. She is married and resides with her family in Ibadan.