Category: Thyroid

THYROID HORMONE STATUS IN DIABETICS: CAN IT BE USED AS PREDICTOR OF GLYCEMIC CONTROL? A CASE CONTROL STUDY AT TERTIARY CARE CENTRE

Monday, Apr 8
1:00 AM – 2:00 AM

Objective :

This study is aimed to study the prevalence of thyroid dysfunction & correlation between glycosylated haemoglobin (HbA1c) and thyroid hormone status (T3, T4, TSH) in Diabetes Mellitus type-2 patients.


Methods :

A case control study of 240 patients, 160 diabetic (as per ADA criteria, age>40) and 80 non diabetic controls recruited as per inclusion/exclusion criteria, was undertaken at tertiary care hospitals of Kota. After detailed clinical & physical examination, all patients were subjected to thyroid profile and HbA1c estimation.


Results :

Hypothyroidism was more common as compared to hyperthyroidism among diabetic patients. Subclinical hypothyroidism constituted 12.5% of cases and clinical hypothyroidism was 5% of cases. Thyroid disorder in diabetics was more common in females (20%) as compared to males (15%). Thyroid disorder among diabetics (i.e. cases) was higher among overweight (27.5%) and obese (15.9%) as compared to those with normal BMI (7.1%). There was negative correlation between HbA1c and T3 level with Pearson correlation coefficient – 0.372 and this correlation was statistically significant (p


Discussion :

Discussion: The association between Diabetes and Thyroid dysfunction has been recognized since 1979.Thyroid hormones are insulin antagonist, both thyroid hormone and insulin are involved in cellular metabolism and excess/deficit of anyone can result in functional derangement of each other.


Conclusion : This study demonstrated that firstly, subclinical hypothyroidism has greater prevalence & second, serum T3 may be reliable index of glycemic control in diabetic patients. Overweight and obese diabetic patients are more prone to subclinical as well as clinical hypothyroidism. These patients with larger waist circumference must be screened for thyroid dysfunction

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G D RAMCHANDANI

Director and Diabetologist RAMCHANDANI DIABETIC CARE AND RESEARCH CENTER
Daswani Dental College KOTA RAJASTHAN INDIA 324005
Kota, Rajasthan, India

Dr. G.D.Ramchandani MD,PGDDM (UK),FACP (USA), FICP, FIACM, AFISC Senior Physician & Consultant Diabetologist Prof. & Head, Dept. of Internal Medicine : Daswani Dental College ,Kota
RAMCHANDANI DIABETES CARE AND RESEARCH CENTER

Approved for IDF : CENTRE OF EDUCATION
Partner of IDF - Project “Life For A Child” at Kota

Fellow American College of Physicians
Post Graduate Diploma in Diabetes Management (PGDDM) from
Middlesex University London (UK)
Hon. Secretary : RSSDI Rajasthan Chapter
Country (INDIA) Advisor of IDF-Project LFAC Medical & Scientific Advisor Group
Tutor of “IDF School of Diabetes”
Joint Secretary ICP (Dean’s Place) 2016
Hon. Secretary : Rajasthan Forum of ICP Fellows
Member Credential Committee of ICP 2016
Sub Editor of “Medicine Update” and “Progress in Medicine” 2016
Member American Association of Clinical Endocrinologists (AACE)
Member: ADA(USA), ATA(USA), ACP(USA), ISPAD(AUSTRALIA),AADE(USA),DSGA,RCP
Regional Faculty and Course Trainer of NDEP and PHFI at Kota
President: API Kota Chapter 2017 ,Kota Diabetic Welfare Trust
National Faculty : APICON, RSSDI, DIACON, HSICON, Diabetes India

Manoj Saluja

Professor Deptt of Internal Medicine Govt Medical College Kota
Govt Medical College Kota

Professor Deptt of Internal Medicine Govt Medical College Kota

Yogesh Swami

Senior Resident Deptt of Internal Medicine GMC Kota Rajasthan
Senior Resident Deptt of Internal Medicine GMC Kota Rajasthan

Senior Resident Deptt of Internal Medicine GMC Kota Rajasthan

K K Pareek

Director and Senior Physician
S N Pareek Hospital Jawahar Nagar Kota Rajasthan

President Association of Physicians of India 2019 , Chairman Scientific Program APICON 2019 held at KOCHI 7-10 Feb, Past Dean Of Indian College of Physicians 2016

GIRISH MATHUR

Director and Senior Physician
S N Pareek Hospital Jawahar Nagar KOTA, Rajasthan, India

Vice Dean Indian College of Physicians , Past Vice President Associatin of Physicians of India