To assess the efficacy of insulin infusion protocol in patients admitted in ICU/Critical care in achieving target blood sugar control (140-180) and its safety in terms of low risk of Hypoglycemia
We have studied 25 patients who received insulin infusion in critical care setting.
In all these patients the incidence of hypoglycemia (< 70 mg/dl) was only 2.55%. 40.02% readings were in the target range (140-180 mg /dl) while the readings in 70-109 mg /dl group and between 110-139 mg/dl group were 9.74% and 20.75 % respectively.
29.17 % of readings were more than 180mg /dl group once target blood glucose level was achieved. This blood glucose level >180mg/dl may be explained by the fact that 58.6 % (17 patients) were receiving steroids and 48.3 %(14 patients) were receiving vasopressors.
The hyperglycemia in patients admitted to critical care is not only difficult to manage but there have been some controversies regarding its management in past years. The target blood glucose of 140-180 is recommended by American diabetes association ADA for patients with critical illness. Similarly, the Society of Critical Care Medicine SCCM also favors BG
TheHypoglycemic events were markedly reduced when insulin infusion was given to patients in an ICU setting and most of the patients remained in the safe glycemic range.
Aga Khan University
My research is focused on diabetes and cardiovascular disease risk reduction, both from primary prevention perspective and improving the clinical care. My initial work on identifying the risk factors of diabetes and cardiovascular disease in Pakistani children and with various socioeconomic backgrounds resulted in several publications.
My current research project is a multinational trial titled “Cardiovascular Disease Risk Reduction Strategies in South Asia (CARRS) – A Translational Trial” focused on impact of non-physician care coordinator and decision support software on reducing the risk factors. My other multinational collaborative work was on the use rapid acting insulin analogs during Ramadan.
I have tried to ask real questions which will have impact on the community, vitamin D deficiency which has resurfaced as a significant health issue, has resulted in my work on identifying best strategy for correcting vitamin D deficiency.
So far I have total 30 publications in peer reviewed journals and I have presented my work locally and internationally.
Aga Khan UniversityHospital, Karachi, Pakistan
currently working as Fellow Endocrinology in Aga Khan University Hospital, Karachi, Pakistan