Category: Other - Vitamin D
Objective : To see the vitamin D status of subjects presented with general weakness .
We studied vitamin D of consecutive 670 patients in a tertiary care hospital. Other variable look for are age, sex, DM and Thyroid function abnormality to see their influence on vitamin D status.
Age, vitamin D of the study population as 95% confidence interval are ( 41.91 – 43.31 years), (18.12 – 19.97 ngm/ml) respectively. Frequency of sex (male) 29.7 % ; diabetic and abnormal thyroid function 31.2% .
Vitamin D status of this subjects are: a) sufficient vitamin D were (>30ngm/ml) in only 10.4 % (n=70); b) deficiency (<20 ngm/ml) in 26.1 % ( n =175 ) and c) insufficient (<30 ngm/ml) in 63.4 % (n = 425) patients.
Comparison between normal (sufficient) vs abnormal (deficient + insufficient) status showed age is significantly higher in sufficient (45.03 – 52.42) vs (41.19 – 43.80) sig. 002; and frequency of DM (50% vs 43%), thyroid Abnormality (33% vs 31%) and sex(male) (29 % vs 30 %) .
Binary logistic regression analysis document population with sufficient vit. D (n 70) different (sig. .003) from the rest (600) when analyzed with age, sex, diabetes & thyroid abnormality as covariates and among these 4 only age significantly influence such equation (sig. .004).
Our study, found 89.6 % subjects have low Vitamin D (<30ngm/ml) among the patients complaining of weakness. Low vitamin D level also found in 56.4 % of non-diabetic and 68.8 % normal Thyroid function. Sex difference was not found to be any role in vitamin D deficiency. Increasing age showed better vitamin D values as they are on regular supplements.
Overall Vitamin D status of our patient with complains of general weakness is poor. It may be reflection of that of our general population and it also urges for more study and adopt appropriate policy on it.
Associate Professor, Endocrinology
Dhaka, Dhaka, Bangladesh
Dr Md Feroz Amin , obtained his bachelor degree from Dhaka Medical College - year 1995, He completed his post graduation on endocrinology , 2005, from BIRDEM academy , under Dhaka University . Presently he working as Associate Professor of Endocrinology in BIRDEM Hospital
Professor Tofail Ahmed presently work in BIRDEM Hospital . He has more than 50 publications in national and international journals .